Pesticide poisoning (organophosphate poisoning)


Description

Most pesticides are organophosphates. Symptoms involve excessive secretions and muscle weakness. If untreated a large exposure can be rapidly fatal due to respiratory failure. 

Symptoms

A SLUDGE syndrome (Salivation, Lacrimation, Urination, Diarrhea, Gastrointestinal upset, Emesis/vomiting), weakness, confusion, poor respiratory effort.

Tests

Common tests used for diagnosis and treatment

Workup:
A history and physical exam will be performed. The diagnosis is made based on the patient's symptoms and a large exposure to pesticides.

Tests:
Pregnancy (BHCG) test, Complete blood count (CBC), Comprehensive metabolic panel (CMP), Electrocardiogram (EKG), Urinalysis (UA), X-ray

Other Specific Tests: RBC cholinesterase in chronic cases, but not acute.

Specialists:
Medical Toxicology

Treatment

Therapy depends on the severity of illness. If serious, treatment may include: intravenous fluids, mechanical ventilation, atropine and pralidoxime (2-PAM).
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