Description
Erythema multiforme is a type of skin rash that has a characteristic target appearance with round, red borders and central clearing. It can occur as a reaction to certain medications, especially antibiotics such as sulfa drugs, or to infections, such as herpes simplex. The rash usually resolves on its own, but it may recur. Some people have frequent episodes. Erythema multiforme can sometimes be associated with a systemic illness called Stevens-Johnson syndrome.
Symptoms
Symptoms include the abrupt onset of a round red rash with raised borders and central clearing. People with Stevens-Johnson syndrome can become very ill with high fever, mouth sores, red eyes, genital sores and liver injury. The rash can progress to blisters, which may be widespread and painful.
Tests
Common tests used for diagnosis and treatment
Workup:
A history and physical will be performed. The diagnosis can usually be made upon examination. Occasionally, a skin biopsy may be required to confirm the diagnosis.
Tests:
Skin biopsy
Specialists:
Internal Medicine, Dermatology, Pediatrics, Family Practice, Telemedicine Dermatology
Workup:
A history and physical will be performed. The diagnosis can usually be made upon examination. Occasionally, a skin biopsy may be required to confirm the diagnosis.
Tests:
Skin biopsy
Specialists:
Internal Medicine, Dermatology, Pediatrics, Family Practice, Telemedicine Dermatology
Treatment
Treatment involves discontinuation of any new medications started within the last two months. Symptoms are treated with acetaminophen (Tylenol), antihistamines and occasionally, topical corticosteroids. Intravenous or oral corticosteroids may be given in more severe cases, but are considered controversial.