Description
Neuroblastoma is the growth of abnormal cells in a specific part of the nervous system called the sympathetic nervous system. It affects infants and children and rarely occurs after age 10. Neuroblastomas develop most commonly in the spine and adrenal glands. However, they can also develop in the chest, neck and pelvis.
Symptoms
Symptoms are related to the location of the tumor. Tumors in the abdomen and adrenal glands can produce abdominal masses, flushing, high blood pressure and diarrhea. Tumors in the spine can produce paralysis, difficulty walking and uncontrollable limb movements. Other symptoms include fever, irritability and difficulty gaining weight.
Tests
Common tests used for diagnosis and treatment
Workup:
A complete history and physical exam will be performed. The diagnosis is often made by imaging tests such as a chest x-ray or CT scan. Ultimately, a tissue biopsy may be required to confirm the diagnosis.
Tests:
Complete blood count (CBC), Comprehensive metabolic panel (CMP), CT Scan, Magnetic resonance imaging (MRI), Urinalysis (UA), X-ray
Other Specific Tests: tissue biopsy
Specialists:
Pediatrics, Pediatric Surgery, Pediatric Hematology and Oncology, Surgical Oncology
Workup:
A complete history and physical exam will be performed. The diagnosis is often made by imaging tests such as a chest x-ray or CT scan. Ultimately, a tissue biopsy may be required to confirm the diagnosis.
Tests:
Complete blood count (CBC), Comprehensive metabolic panel (CMP), CT Scan, Magnetic resonance imaging (MRI), Urinalysis (UA), X-ray
Other Specific Tests: tissue biopsy
Specialists:
Pediatrics, Pediatric Surgery, Pediatric Hematology and Oncology, Surgical Oncology
Treatment
Treatment is determined by the size and location of the cancer. A combination of surgery, chemotherapy and radiation therapy may be used.