Sickle cell crisis (complication of sickle cell disease)



Description

Occurs in patient with sickle cell disease when sickled red blood cells clog blood vessels. Sickle cell disease is the most common of the inherited blood disorders. A sickle cell crisis causes pain because blood vessels become blocked and the defective red blood cells can damage organs in the body. The most commonly affected organs include: lungs, liver, bone, muscles, brain, spleen, penis, eyes, and kidneys.

Symptoms

Chest pain, breathing problems, weakness, seizures, confusion, weak pulse, abdominal pain, coma.

Tests

Common tests used for diagnosis and treatment

Workup:
A history and physical exam will be performed. Blood tests to detect the severity of the anemia and the ability to produce red blood cells will be performed. Other tests to identify the damage done by the sickle cell crisis will be done.

Tests:
Complete blood count (CBC), Comprehensive metabolic panel (CMP), CT Scan, Electrocardiogram (EKG), Lipase, Magnetic resonance imaging (MRI), Troponin, Urinalysis (UA), Ultrasound, X-ray

Other Specific Tests: Reticulocyte count

Specialists:
Blood and Cancer Care (hematology and oncology), Pediatric Hematology and Oncology

Treatment

Treatment includes: intravenous fluids, supplemental oxygen, pain medications, antibiotics (if infection is found), and/or blood transfusions.
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